1789, Recollect fathers under Fr. Julian de Nuestra Señora del Mayor Dolor, took over the Misamis mission: established the parish of the Immaculate Conception; Fr. Constancio Arsenio, opened a little school in his convento, later became the Immaculate Conception College; classes were the Cartilla, the Misterio, the Tresagia and the Novena (equivalent to grade six). Upon the completion of the Novena, students were qualified to teach the lower grades. This type of parish school continued into the early years of the American regime.
1919: Jesuits returned to Misamis, replaced the Recollects
1929: under Fr. Gabriel Font S.J., the Immaculate Conception School (ICS) formally established an elementary school. Thirty pupils were registered with Mr. Juan Fuentes and his sister Cirila, as teachers. 1929 marked the formal founding of the Immaculate Conception College although actual government recognition for the elementary course would not come until 1935.
1939: Society of St. Columban took over the parish from the Jesuits: Fr. Peter Fallon became the first Director of the Immaculate Conception School and first graduation of ICS.
1941: Columban Sisters administered ICS, at the invitation of Bishop James Hayes and the Columban Fathers: Sr. Francis De Sales, Directress, Sr. Mary Teresa and Sr. Mary Campion, Sr. Attracta, a nurse, took charge of the school clinic, followed later. World War II broke out and classes had to be discontinued. Japanese army converted the old convento school building into their headquarters.
1945: classes resumed with Sr. Teresa as Directress. Enrollment increased, lay faculty members were added and more Columban Sisters arrived.
1948: High School Department held its first graduation exercises 1948, June, Mother Mary Theopane opened the college department with 18 students. Old convento was replaced by a one-storey building.
1950 – 1980: Elementary and High School Departments were transferred to a four-hectare site. Spacious three-storey building, an Arts Center, a chapel and a canteen were built. Another four hectare lot across the Elementary and High School Campus was purchased to allow further development. Course offered range from Nursery to Ph.D.
1987: Bishop Federico Escaler, S.J., D.D. became the President of Immaculate Conception College at the request of the Columban Sisters.
1990: at the request of the Columban Sisters, the De La Salle Brothers assist in the academic supervision of the school. Brother Martin Simpson FSC, became the Supervisor and later the President.
1992: Liberal Arts, Education and Commerce were granted Level 1 by PAASCU (Philippine Accrediting Association of Schools, Colleges and Universities), an acknowledgement of the school’s desire to attain high standard of quality education.
1994: May 17, De La Salle Brothers take over the ownership and management of Immaculate Conception College. Sr. Ann Rita Centino, SSC, Provincial Superior of the Missionary Sisters of St. Columban in the Philippines and Br. Benildo Feliciano FSC, Provincial Superior of the De La Salle Brothers in the Philippines were present.
1995: Dr. Emma Villaresan, installed as the first lay President. College was granted Level II by PAASCU for a period of three years.
1998, March, Br. Benildo Feliciano FSC, became President. Led the school to actively take part in the national, political and socio-economic affairs and issues. PAASCU Level II Reaccredidation for a period of five years.
2003, May, Br. Narciso Erguiza Jr. FSC became the Third President. New major subjects were offered in addition to the new program offerings. PAASCU Level II Third Resurvey for a period of five years.
2005, May, High School Department applied for PAASCU Accreditation and granted Level I status.
2005, June, formally launched the Integrated School (Grade School and High School) as a unified unit.
2006, February, Grade School Department applied and granted PAASCU Level I status.
2006, June, new Integrated School building was ready for occupancy for Grades 5 – 10.
2006, September, the school was granted UNIVERSITY STATUS; ICC – La Salle became LA SALLE UNIVERSITY – OZAMIZ.
2007, June, La Salle University Integrated School Campus finally accommodated all grade levels from Kindergarten to Grade 10 with the construction of 8 new classrooms at the 4th floor.
2007, November 23, Integrated School as Basic Education granted Level II by PAASCU for a period of 3 years.